NF-κB
NF-κB is important in regulating cellular responses because it belongs to the category of "rapid-acting" primary transcription factors, i.e., transcription factors that are present in cells in an inactive state and do not require new protein synthesis in order to become activated (other members of this family include transcription factors such as c-Jun, STATs, and nuclear hormone receptors). This allows NF-κB to be a first responder to harmful cellular stimuli. Known inducers of NF-κB activity are highly variable and include reactive oxygen species (ROS), tumor necrosis factor alpha (TNFα), interleukin 1-beta (IL-1β), bacterial lipopolysaccharides (LPS), isoproterenol, cocaine, and ionizing radiation.
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Bardoxolone(RTA 402)是抗氧化炎症调节剂（AIM）的先导化合物。
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SP 100030是NF-κB，AP-1双效抑制剂。
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Ro 106-9920是Ro 106-9920 is a NF-κB activation inhibitor 。
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Pyrrolidinedithiocarbamate ammonium是Pyrrolidinedithiocarbamate ammonium inhibits NF-κB and prevents increase in NOS mRNA.。
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PSI
EI2265
PSI是蛋白酶体抑制剂，可以抑制NF-κB的激活。
More
-
Bardoxolone(RTA 402)是抗氧化炎症调节剂（AIM）的先导化合物。
More
-
SP 100030是NF-κB，AP-1双效抑制剂。
More
-
Ro 106-9920是Ro 106-9920 is a NF-κB activation inhibitor 。
More
-
Pyrrolidinedithiocarbamate ammonium是Pyrrolidinedithiocarbamate ammonium inhibits NF-κB and prevents increase in NOS mRNA.。
More
-
PSI
EI2265
PSI是蛋白酶体抑制剂，可以抑制NF-κB的激活。
More
